Services

Clinical and Genomic Software Development and Implementation

The Core has designed, developed and implemented clinical databases for various cancer groups at LCCC. Based on the Vanderbilt University MetaClinic system, the Core has developed clinical applications for the Breast, GI, and Head and Neck tumor types. The Core has also designed, developed and implemented an online tissue-tracking system for the Tissue Procurement Facility. These systems are all based on Oracle Forms and Reports. The LCCC Genomics Core hosts the UNC Microarray Database, which is a relational database that stores thousands of individual microarray experiments and has build in data analysis tools. Originally based on the Stanford Microarray Database, the UNC MD has been customized to meet local cancer researcher needs and is constantly under development. The Lineberger Bioinformatics Group also has a dedicated microarray data analyst whom is available to help in all aspects of microarray data analysis. The Core also provides software evaluation and implementation support for various groups at LCCC. Currently, the group has implemented a LIMS system for the LCCC Genomics Core, and for the Mammalian Genotyping Core.

Data Analysis Services

The Core provides statistical and computational analysis and experimental design services for cancer research. The core has developed computational tools for microarray data analysis including software packages for Distance Weighted Discrimination and Single Sample Prediction. The Core also helps in data analysis using software like Cluster, Treeview and various Bioconductor packages and can train researchers on how to use these, and many other genomic data analysis packages.